The APCO Bone Health QI Tool Kit – Putting a brake on fractures in the world’s most populous & fastest ageing region

An osteoporotic fracture occurs every three seconds worldwide. With more than 50 per cent of the world’s hip fractures expected to occur in the Asia Pacific (AP) region over the next two decades, the Asia Pacific Consortium on Osteoporosis (APCO) has launched a Bone Health QI Tool Kit today (May 24, 2022), to promote quality improvement (QI) of osteoporosis care.

Asia Pacific Consortium on Osteoporosis (APCO) launched a comprehensive Bone Health QI Tool Kit today to promote quality improvement (QI) of osteoporosis care. (May 24, 2022)

This comprehensive tool kit, that encompasses multiple components in the screening, diagnosis and management of osteoporosis, is a world-first of its kind, said Dr Manju Chandran, APCO Chairperson and Director of the Osteoporosis and Bone Metabolism Unit, Singapore General Hospital, Singapore.

“Previous audits have focused on just a single aspect of osteoporosis care, namely the identification and appropriate management of osteoporotic fragility fractures. A perfect storm of a rise in osteoporosis among Asia-Pacific populations is expected to occur due to the region’s rapidly ageing population, mounting urbanisation, and subsequent increase in sedentary lifestyles,”2 Dr Chandran said.

“A recent analysis of nine Asian countries and regions reveals the number of hip fractures will more than double from 1.13 million in 2018, to 2.54 million in 2050,3 primarily due to changing population demographics.”

The APCO Bone Health QI Tool Kit is based on seven selected standards from The APCO Framework that apply to the clinical setting. Implementation of the QI will be through iterative Plan-Do-Study-Act (PDSA) cycles.

“Once the audits are completed, healthcare professionals (HCPs) and medical centres can commence implementing changes to their clinical practice. APCO is in the process of engaging QI experts to help train APCO members to perform such projects in their individual medical centres and practices,” said Dr Chandran.

The tool kit will enable these auditing exercises to be undertaken to establish levels of adherence with those standards of care within The APCO Framework that can be implemented directly into clinical practice.4

This year in Australia, an estimated 6.2 million people aged over 50 years will be living with osteoporosis or osteopenia, representing a 31 per cent increase from 2012,5 said Dr Greg Lyubomirsky, CEO, Healthy Bones Australia.

“The likelihood of successfully creating change to stem this bone health crisis will rest largely upon the efforts of HCPs to engage their peers to work towards shared goals. Articulating the benefits of the APCO Bone Health QI activity can help promote engagement and cooperation.

“The critical factors to success include having a supportive organisational culture, good design and planning, and follow through on results, ensuring the data collection is meaningful and achievable,” Dr Lyubomirsky said.

“Data collected through the audit should be used to benchmark practice against the standards recommended by The APCO Framework. This will show stakeholders that the audit was worth the effort, and that it contributed to tangible change.”

The APCO audit focuses on investigating the patient pathway, identifying the gaps or missed opportunities for patients at risk, and then the PDSA activity is used to improve quality of care and to formulate recommendations.

“It is hoped that lessons from implementing these clinical standards at the institutional level will be key to achieving change at the national level, through the development, or revision of national guidelines, and policy change,” said Dr Philippe Halbout, CEO, International Osteoporosis Foundation, Switzerland.

“These coordinated systems of care aim to identify, treat and monitor patients with osteoporosis. Timely intervention can reduce fractures by up to 50 per cent, deliver substantial financial savings, and ultimately, save lives.”

Osteoporosis is greatly under-diagnosed and under-treated in Asia, even among those at highest risk who have already fractured.6

The APCO Bone Health QI Tool Kit focuses on closing this gap by:

— Understanding the baseline variables and current state of osteoporosis care in any given institution or health care practice.
— Enabling benchmarking clinical practice against The APCO Framework, evidence-based clinical practice guidelines or established protocols for the chosen standard of care.
— Using the findings to then improve the quality of care through iterative PDSA cycles.
— Using the lessons learned from implementation of the APCO Clinical Standard at an institutional level, to build momentum and work towards inclusion of the quality improvement/clinical standard in national guidelines, and lobbying for funding and policy change, as appropriate.

Practically, PDSA cycles are a quality improvement strategy that tests a change on a small scale. The PDSA builds on the learning from test cycles in a structured way before implementation on a wider scale.7

The PDSA cycles are iterative. Each cycle involves the following four stages:
1. Plan — developing a plan to test the change;
2. Do — carrying out the test;
3. Study — observing and learning; and
4. Act — planning the next change cycle or full implementation.

“Assessment of adherence to pharmacological treatments that are recommended in new or revised osteoporosis clinical guidelines should be undertaken on an ongoing basis, after initiation of therapy, and appropriate corrective action can be taken if treated individuals have become non-adherent,” Dr Chandran advised.

Every patient living with osteoporosis and/or a fragility fracture passes through several points on their journey from diagnosis, through to treatment and follow-up. The interface of this pathway with other entities, for example, referrals to other care givers or departments, post- discharge follow-ups, are also important considerations in the quality of care received.

“The launch of the APCO Bone Health QI Tool Kit demonstrates the organisation’s ongoing commitment to achieving better care for patients with greater consistency in national and regional clinical practice guidelines for the screening, diagnosis, and management of osteoporosis in the Asia Pacific,” said Dr Halbout.

To learn more about the APCO Bone Health QI Tool Kit,
visit www.apcobonehealth.org or follow APCO on LinkedIn: asia-pacific-consortium-on-osteoporosis.

About the APCO Bone Health QI Tool Kit

APCO developed the Bone Health QI Tool Kit to enable healthcare providers worldwide, to benchmark their practices against the clinical standards proposed in The APCO Framework. The tool kit provides guidance on undertaking and implementing quality improvement (QI) projects centred around seven key clinical standards for the screening, diagnosis, and management of osteoporosis.

With the key objective of promoting QI of osteoporosis care, the APCO audit focuses on investigating the patient pathway, identifying the gaps, or missed opportunities for patients at risk, and formulating recommendations to address these gaps. Implementation of the QI will be through Plan-Do-Study-Act (PDSA) cycles – a quality improvement strategy that tests a change on a small scale, before implementation on a wider scale. The tool kit offers practical tips on conducting an audit, that generates meaningful data, that can lead ultimately to implementing changes in clinical practices.

About APCO

The Asia Pacific Consortium on Osteoporosis (APCO) comprises 46 osteoporosis experts from 20 countries and regions, charged with developing tangible solutions to the substantive challenges involving osteoporosis management and fracture prevention in this most populated and fastest growing part of the world. APCO’s mission is to engage with relevant stakeholders, including healthcare providers, policy makers and the public, to help develop and implement country and region-specific programs for the prevention and treatment of osteoporosis, and its complication of fragility fractures, in the Asia Pacific. https://www.apcobonehealth.org

About osteoporosis in the Asia Pacific region

* Osteoporosis – the most common disease – is characterised by porous and brittle bones whose density and quality are poor, resulting in structural skeletal deterioration.1
* The Asia Pacific is home to 4.5 billion people with vastly different healthcare systems.8
* In most developing countries of the Asia Pacific, especially in rural areas, DXA technology is not widely available.9
* Low levels of vitamin D are observed region-wide in the Asia Pacific. This can be attributed to several causal factors, including genetic, lifestyle, seasonal and geographical influences.10
* More than 68 per cent of the countries in the IOF’s Asia Pacific’s Regional Audit now have populations that are over 50 per cent urban, and the resulting reduction in sunlight exposure due to pollution and overcrowding, is affecting vitamin D levels, which contribute to osteoporosis risk.10
* Nearly all Asian countries fall far below The Food and Agriculture Organization of the United Nations / World Health Organization (WHO) recommendations for calcium intake of between 1,000 and 1,300 mg/day. The calcium intake for Malaysia, the Philippines and India remains below 500 mg/day.10

DIGITAL MEDIA KIT: www.apcotoolkit.org

Asia Pacific Consortium on Osteoporosis (APCO)
secretariat@apcobonehealth.org

References
1. International Osteoporosis Foundation (IOF). Capture the fracture. [Oct, 2021]; https://www.capturethefracture.org/about.
2. Chandran M, et al., Development of the Asia Pacific Consortium on Osteoporosis (APCO) Framework: clinical standards of care for the screening, diagnosis, and management of osteoporosis in the Asia-Pacific region. Osteoporos Int., 2021. 32(7): p. 1249-1275.
3. Cheung, C.-L., et al., An updated hip fracture projection in Asia: The Asian Federation of Osteoporosis Societies study. Osteoporosis and sarcopenia, 2018. 4(1): p. 16-21.
4. Chandran, M., Ebeling, P., Mitchell, P., Nguyen, T., Harmonization of Osteoporosis Guidelines: Paving the Way for Disrupting the Status Quo in Osteoporosis Management in the Asia Pacific. JBMR, 2022.
5. Watts, J., Ambimanyi-Ochom, J, & Sander K, Osteoporosis costing all Australians: A new burden of disease analysis 2012-2022. 2013, Osteoporosis Australia.
6. International Osteoporosis Foundation (IOF). Key statistics for Asia. [cited October 2021]; https://www.osteoporosis.foundation/facts-statistics/key-statistic-for-asia.
7. NHS England and NHS Improvement. Plan, Do, Study, Act (PDSA) cycles and the model for improvement. https://www.england.nhs.uk/wp-content/uploads/2022/01/qsir-pdsa-cycles-model-for-improvement.pdf.
8. Wang, P., et al., Estimation of Prevalence of Osteoporosis Using OSTA and Its Correlation with Sociodemographic Factors, Disability and Comorbidities. International Journal of Environmental Research and Public Health, 2019. 16(13): p. 2338.
9. Chandran, M., et al., IQ driving QI: the Asia Pacific Consortium on Osteoporosis (APCO): an innovative and collaborative initiative to improve osteoporosis care in the Asia Pacific. Osteoporos Int, 2020. 31(11): p. 2077-2081.
10. International Osteoporosis Foundation (IOF). The Asia-Pacific Regional Audit. 2013 [cited May 2022]; https://www.osteoporosis.foundation/sites/iofbonehealth/files/2019-06/2013_Asia_Pacific_Audit_English.pdf

Launch of world-first expert resource to foster best practice osteoporosis care in the Asia Pacific

More than 50 per cent of the world’s hip fractures are expected to occur in the Asia Pacific by the year 2050.

In a strong effort to stem the tide, and to promote quality care in osteoporosis, the Asia Pacific Consortium on Osteoporosis (APCO) has launched a world-first, interactive, educational osteoporosis resource – the APCO Health Care Professional (HCP) Peer to Peer Educational Modules – today, to mark World Osteoporosis Day (Wednesday, October 20).

The survival of those who sustain an osteoporotic fragility fracture is significantly compromised for up to six years, with patients facing twice the risk of death within the first year. Furthermore, a prior fracture at any site doubles a person’s risk of refracture. Yet despite these alarming statistics, more than 80 per cent of fragility fracture patients are neither assessed, nor treated, placing a substantial, but importantly, preventable burden on already strained healthcare systems. This is despite the extensive availability of safe and effective osteoporosis management strategies.

Minimum clinical standards for the assessment and management of osteoporosis are therefore urgently required in the Asia Pacific, to inform clinical practice guidelines, and improve osteoporosis care. It was with this aim in mind that APCO launched ‘The APCO Framework’ in January, 2021. ‘The Framework’ comprises 16 minimum clinical standards that serve as a benchmark for the provision of best practice osteoporosis care in the Asia Pacific.

The APCO HCP Peer to Peer Education Modules will offer physicians a comprehensive, evidence-based resource encouraging widescale implementation of the minimum clinical standards of care for osteoporosis advocated in The APCO Framework. This will enable the delivery of best practice osteoporosis care throughout the Asia Pacific – the world’s fastest ageing region.

According to APCO Chairperson, and Director of the Osteoporosis and Bone Metabolism Unit, Singapore General Hospital, Dr Manju Chandran, Singapore, there are significant inconsistencies in clinical practice guidelines in the Asia Pacific for the management and prevention of osteoporosis and fragility fractures. These guidelines vary extensively in scope and recommendations. There is also a lack of information available on adherence to national guidelines in daily clinical practice.

“It is to address this care gap, that APCO has developed an interactive, 17-module educational series today, to arm osteoporosis champions in the Asia Pacific, with information, supporting data, topical literature summaries, and best practice examples that support and emphasise each of The APCO Framework’s 16 minimum clinical standards and emerging themes in osteoporosis care.

“Increasing awareness and education among healthcare professionals in the Asia Pacific is imperative to bringing change to the real-world clinical practice of osteoporosis care and fracture prevention,” said Dr Chandran.

“The Asia Pacific is home to 4.5 billion people, rapidly ageing populations, and vastly different healthcare systems.

“An overwhelming 319 million people aged 50 years and over from the Asia Pacific are projected to be at high risk of osteoporotic fracture over the next two decades, while more than half of the world’s hip fractures are expected to occur in the region by 2050,” Dr Chandran said.

“Singapore, where I live, for instance, has one of the highest hip fracture rates in the world, with a four-to-five-fold increase in incidence noted over a recent 30-year period.

“The incidence of osteoporotic fractures in Singapore is projected to rise from more than 15,000 in 2017, to 24,100 by 2035, an increase of 57.9 per cent. The total economic burden (including both direct and indirect costs) associated with these fractures is projected to grow from SGD 183.5 million (USD 214 million) in 2017, to SGD 289.6 million (USD 136 million) by 2035.”

After one year, two in five people who sustain a hip fracture will be unable to walk independently, while two-thirds will encounter difficulty performing at least one essential daily task.

“Economically, the burden of current treatment of a single hip fracture in the Asia Pacific is extremely high, equating to approximately 19 per cent of our region’s per-head gross domestic product (GDP),” said APCO Committee member, Consultant in Endocrinology and Diabetes at Tun Wah Hospital, and Chairperson of the Guideline for the Management of Postmenopausal Osteoporosis in Hong Kong, Dr Ip Tai-Pang,Hong Kong SAR.

In Hong Kong SAR alone, the direct medical costs of hip fractures was an estimated USD 85 million in 2018, the costs for which are projected to increase to USD 243 million by 2050.

“Given the anticipated exponential growth in fragility fractures due to the region’s rapidly ageing population, mass urbanisation and our increasingly sedentary lifestyles, we must act now,” Dr Ip said.

“Osteoporosis experts can use the new APCO HCP Education Modules either in full, or in part, to inspire and further inform their peers and professional communities on those at high-risk for fracture who require identification and assessment, based on their medical and fracture history, risk factors, co-occurring diseases, country-specific osteoporosis screening tool results, and falls risk.

“Supporting data on the administration, duration, monitoring of, and adherence to, various treatment interventions and their associated side-effects, as well as the critical need for long-term management plans, also feature in the APCO modules,” said Dr Ip.

Osteoporosis is vastly under-diagnosed and under-treated. Disturbingly, millions of people worldwide at high risk of fracture remain unaware of this underlying, silent disease. Championed by the International Osteoporosis Foundation (IOF), World Osteoporosis Day is dedicated to raising global awareness of the importance of prevention, diagnosis and treatment of osteoporosis and musculoskeletal diseases.

“This World Osteoporosis Day, we encourage healthcare providers, policy makers, patients, members of the public, and the media on a global, regional and national stage, to recognise the monumental human and socio-economic burden of osteoporosis, and the severe impact of fractures on a patient’s independence and quality of life,” IOF Chief Executive Officer, and APCO Executive Committee member, Dr Philippe Halbout, Switzerland said.

“One of the emerging osteoporosis themes outlined in the APCO HCP Education Modules, is the importance of Asia Pacific-wide systemic integration of case identification and management at all levels of health systems, including acute care services, when patients present with fractures through Post Fracture Care Coordination Programs, such as Fracture Liaison Services (FLS).

“These coordinated systems of care aim to identify, treat and monitor patients presenting with a fragility fracture. Intervention can reduce fractures by up to 50 per cent, deliver substantial financial savings, and ultimately, save lives,” said Dr Halbout.

“Today’s launch of the APCO Education Modules demonstrates the organisation’s ongoing commitment to achieving greater consistency in national and regional clinical practice guidelines for the screening, diagnosis, and management of osteoporosis in the Asia Pacific.”

To request access to The APCO Education Modules, head to: apcobonehealth.org/apco-education-modules.
To learn more, visit www.apcobonehealth.org or follow APCO on LinkedIn:asia-pacific-consortium-on-osteoporosis.

About APCO
The Asia Pacific Consortium on Osteoporosis (APCO) comprises osteoporosis experts from 19 countries in the Asia Pacific, charged with developing tangible solutions to the substantive challenges involving osteoporosis management and fracture prevention in this most populated and fastest growing part of the world. APCO’s mission is to engage with relevant stakeholders, including healthcare providers, policy makers and the public, to help develop and implement country and region-specific programs for the prevention and treatment of osteoporosis, and its complication of fragility fractures, in the Asia Pacific.

About osteoporosis in the Asia Pacific region
– Osteoporosis is estimated to account for nearly nine million fractures each year, noting more than 200 million people worldwide live with osteoporosis.
– Osteoporotic fractures among Asia-Pacific populations are expected to increase exponentially, due to the region’s rapidly aging population, mounting urbanisation, and subsequent increase in sedentary lifestyles.
– Osteoporosis is greatly under-diagnosed and under-treated in Asia, even among those at highest risk who have already fractured. In most developing countries of the Asia Pacific, especially in rural areas, DXA technology is not widely available.

About World Osteoporosis Day
Falling each year on October 20, World Osteoporosis Day raises awareness of bone health and osteoporosis prevention. This year’s campaign, under the banner of ‘Take Action for Bone Health’, calls for global action to fight osteoporosis and related fractures. See: www.worldosteoporosisday.org.